Active Projects
Updated: Nov-7-06
Biochemistry
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Cadilla, Carmen PhD | Molecular Genetics of Hermansky Pudlak Syndrome in Puerto Rico | Outpatient |
| Cadilla, Carmen PhD | Identification of the gene(s) responsible for type III focal facial Displasia (Setleis Syndrome) (Pilot Project) | Administrative Support |
| Irizarry-Ramírez, Margarita PhD | Proteomic Analysis of the Sera of Prostate Cancer in Hispanics Patients. | Laboratory Biostatistical Support |
| Rodríguez Orengo, José PhD | Prevalence of GSTM1, T1, and P1 in Hispanics | Laboratory Biostatistical Support |
Cardiology
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INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Banchs-Pieretti, Héctor L. MD | A 24-month, multi-center, Randomized, open-label non-inferiority study of efficacy and safety comparing two exposures of concentration -controlled Certain with reduced Neoral versus 3.0 g MMF with standard dose Neoral in the novo heart transplant recipients. | Laboratory |
| Banchs-Pieretti, Héctor L. MD | Basiliximab Induction Therapy in Heart Transplantation.. The experience in Puerto Rico. | Biostatistical Support |
| García-Palmieri, Mario MD | Atrial Fibrillation and Congestive heart Failure (AF-CHF) | Outpatient |
Dentistry
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Bermúdez, Francisco DMD, PhD | Oral Cancer Detection: Current and Emerging Technologies |
Outpatient Laboratory |
| Morou, Evangelina DDS, MS, PhD | K-23: Urease Activity and Dental Caries in Children |
Biostatistical Support Outpatient Laboratory |
| Toro, Edgardo J. DMD | The effect of sugar on the levels of Urease activity in plaque and in saliva in vivo. |
Outpatient Laboratory Biostatistical Support |
Emergency Medicine
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INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Lugo, Nannette MD | In Hospital Cardiac Arrest Management Evaluation in an Teaching Hospital in Puerto Rico. | Biostatistical Support |
| Lugo, Nannette MD | Out of Hospital Cardiac Arrest Management Evaluation in North East Region of Puerto Rico. | Biostatistical Support |
Gastroenterology
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INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Cruz Correa, Marcia MD, PhD | Epidemiology of Loss of Imprinting in Colorectal Cancer |
Biostatistical Support Laboratory Patient Coordinator Outpatient |
| Romero-Marrero, Carlos J. MD | Role of risk factors and novel biomarkers in the development and early detection of hepatocellular carcinoma. (Pilot Project) |
Biostatistical Support Laboratory Patient Coordinator |
| Torres, Esther A. MD | Retrospective Study of the Management of Esophageal Varices in Cirrhotic Patients Evaluated at ASEM Emergency Room and the University Hospital | Biostatistical Support |
| Torres, Esther A. MD | Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor as an Alternative Therapy for Fistulizing Crohn's Disease | Biostatistical Support |
| Torres, Esther A. MD | Inflammatory Bowel Disease Patient Serum Bank | Laboratory |
| Torres, Esther A. MD | Anemia in Patient with Ulcerative Colitis and Ileal Pouch. | Biostatistical Support |
| Torres, Esther A. MD | Mapping Genes for IBD in Puerto Ricans |
Outpatient Biostatistical Support Laboratory |
Geriatrics
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INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Jiménez, Ivonne MD | A Study of Risk Factors for Alzheimer's Disease and Related Disorders in the Caribbean Hispanic Population in Puerto Rico |
Outpatient Laboratory |
Gynecologic
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INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Laras, Linda MD, MPH, FACOG | Women's Cardiovascular Risk and Violent Experience |
Biostatistical Support Laboratory Outpatient |
| Romaguera, Josefina MD, MPH | A Prospective, Open-Label, Multicenter Study to Evaluate the Change in Bone Turnover Markers After Once Monthly Oral Ibandronate Therapy in Treatment naïve Postmenopausal Osteoporosis Patients. | Laboratory |
| Romaguera, Josefina MD, MPH | Menopause and Health in Hispanic Women in Puerto Rico |
Biostatistical Support Laboratory |
| Romaguera, Josefina MD, MPH | Immunogenicity and Safety of Quadrivalent HPV (Types 6, 11, 16, 18) I1 Virus-Like Particle (VLP) Vaccine in Consistency Lots for 16 to 23 Year Old Women with an Additional Immunogenicity Bridge to the Monovalent HIPV 16 Vaccine Pilot Manufacturing Lot - The F.U.T.U.R.E. Study (Females United to Unilaterally Reduce Endo-Ectocervical Disease) | Laboratory |
Infectology
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Santana, Jorge L. MD | A Phase 2, Randomized Study of the Treatment of Antiretroviral Treatment-Experienced, HIV-1 Infected Subjects Comparing Ritonavir-Boosted GS-9137 (GS-9137/r) Versus a Comparator Rotinavir-Boosted Protease Inhibitor (CPI/r) in Combination with a Background Antiretroviral Therapy (GS-US-183-0105) | Outpatient |
| Santana, Jorge L. MD | A Phase IIIB, Randomized, Trial of Open-Label Efavirenz or Atazanavir with Rotonavir in Combination with Double-Blind Comparison of Emtricitabine/Tenofovir or Abacavir/Lamivudine in Antiretroviral-Naïve Subjects (A5202) | Outpatient |
| Santana, Jorge L. MD | Suppressive Long-Term Antiviral Management Of Hepatitis C Virus (HCV) And HIV-1 Coinfected Subjects (SLAM-C) (A5178) | Outpatient |
| Santana, Jorge L. MD | A Phase II Randomized Controlled Trial Evaluating The Impact of Therapeutic Drug Monitoring (TMD) On Virologic Response To A Salvage Regimen In Subjects With A Normalized Inhibitory Quotient (NIQ) ? 1 to One Or More Protease Inhibitors (A5146) | Outpatient |
| Santana, Jorge L. MD | An Open-Label, Dose-Escalation Pilot Study Of Acetyl-L-Carnitine For The Treatment Of Dideoxynucleside-Associated Distal Symmetric Peripheral Neuropathy (A5157) | Outpatient |
| Sariol, Carlos MD, PhD | Factors Associated to HCV-Chronic Liver Damage in Hispanics. | Biostatistical Support |
| Sariol, Carlos MD, PhD | Association of Viral Genome diversity, Cytokine Profile and Genetics Polymorphisms to the histologic Progression of Chronics Hepatitis C |
Outpatient Laboratory |
Internal Medicine
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Rodríguez, Vanessa E. MD | A Randomized, Double Blind, Parallel group study of the safety and prevention of structural joint damage during treatment with MRA versus placebo, in combination with methotrexate, in patients with moderate to severe active rheumatoid arthritis. |
Outpatient Laboratory |
Microbiology
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Espino, Ana PhD | Immune Response in mice after vaccination with a novel F.Hepática vaccine | Biostatistical Support |
| Irizarry, Margarita PhD | Relation between Body Mass Index, PSA Level and Prostate Cancer | Biostatistical Support |
| Meléndez, Loyda PhD | Monocyte Immunity in HIV Induced Dementia | Outpatient |
Neonatology Pediatrics
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| García, Lourdes MD | MTHFR mutations and Homocysteine in Children with Congestive Heart Disease |
Biostatistical Support Laboratory |
| García, Lourdes MD | Folate and Homocysteine Levels in Puerto Rican Women after Mandatory Folic Acid Supplementation of Grain Derived Products |
Biostatistical Support |
| Valcárcel, Marta MD | Early Identification of Stroke and/or Intraventricular Hemorrhage Grade III/IV in Newborns of <=1500 Grams Born in Puerto Rico will Facilitate the Identification of Prothrombotic Disorders in the Neonate |
Biostatistical Support |
Nephrology
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Burgos Calderón, Rafael MD | Chronic Kidney Disease at University of Puerto Rico of Medicine Nephrology Clinics. A multivariable description study using a proposed modified National Kidney Diseases Foundation Classification of Chronic Kidney Disease. | Biostatistical Support |
| Burgos Calderón, Rafael MD | The Collaborative Study Group Trial: Defect of Sulodexide in Overt Type 2 Diabetic Nephropathy (KRX 101-401) |
Laboratory Patient Coordinator Outpatient |
| Burgos Calderón, Rafael MD | The Collaborative Study Group Trial: Defect of Sulodexide in Patient with Type 2 Diabetes and Microalbuminuria (KRX 101-301) |
Laboratory Patient Coordinator Outpatient |
| Burgos Calderón, Rafael MD | Diabetes Reduction Assessment with Ramipril and Rosiglitazone Medication - A Randomized Placebo Controlled Trial |
Laboratory Patient Coordinator Outpatient |
| Burgos Calderón, Rafael MD Montalvo, Lisandro MD |
The role of inflammatory cytokines and oxidative stress and the effect of angiotensin II blockadeon diabetic neuropathy | Biostatistical Support |
Neumology
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| De Jesús, Yohanna MD | Validation of the Spanish Version of the Medical Research Council Scale, Basal Dyspnea Index, Oxygen Cost Diagram, and the San Diego Shortness of Breath Questionnaire in a Hispanic Population | Biostatistical Support |
| Dexter, Donald MD | Effect of b-agonist on QT Interval in Normals and in Subjects with Pulmonary Obstructive Disease | Biostatistical Support |
Neurology
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Fiol, Miguel MD | Comparison of Health Services received by Epilepsy Patients under the Public Health Reform System and Private Insurance in the Island of Puerto Rico | Biostatistical Support |
| Luciano, Carlos A. MD | HIV Sensory Neuropathy: Age Risk Factors and Immunopathogenesis |
Outpatient Laboratory Biostatistical Support |
| Luciano, Carlos A. MD | Clinical Trial of IGF-I in Patients with Amyotrophic Lateral Sclerosis (ALS) |
Outpatient |
| Luciano, Carlos A. MD | A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-Center Trial of Pregabalin vs Placebo in the Treatment of Neuropathic Pain Associated with HIV Neuropathy |
Outpatient |
| San Miguel-Montes, Lisa Psy. D | Developmental Study of a Hispanic Pediatric Cohort diagnosed with Neonatal Seizures: Long term outcomes of General Intelligence and Visual Motor Functions. |
Biostatistical Support |
| San Miguel-Montes, Lisa Psy. D | Biochemical Performance, Biochemical and Microestructural Changes at Early Stages of Relapsing Remitting Multiple Sclerosis. (Pilot Project) |
Biostatistical Support Patient coordinator Outpatient Administrative services |
| Santiago Castillo, Fernando L. MD | Insulin Resistance Intervention Stoke (IRIS Trial) |
Outpatient Laboratory |
| Serrano, Carmen MD | Study of Antidepressants in Parkinson Disease | Outpatient |
| Serrano, Carmen MD | An Active Extension of the TVP-1012/133 Study A Binational Double-Blind, Randomized Study to Evaluate the Safety and Tolerability of Rosagiline Mesylate in Advanced PD Patients with Motors Fluctuations Treated with Chronic Levodopa/Carbidopa Therapy TVP - 1012/135 |
Outpatient Laboratory |
| Vélez-Borrás, Jesús R. MD | Long Term, Open-Label, Safety Study of Tomoxetine Hydrochloride in Patients, 6 Years or Older (LYAI) |
Outpatient Laboratory |
| Wojna, Valerie MD | Pathophysiology of HIV Dementia in Woman | Outpatient |
Nursing
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Regueira, Yadira RN, PhD | Genetic Determinants of Lypodistrophy in HIV-positive patients |
Outpatient Laboratory |
Orthopedic
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Valenzuela, Richard MD | Hepatitis C Virus as a Risk Factor for Osteonecrosis. | Biostatistical Support |
Otolaryngology Pharmacology
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Maeso, Patricia MD Baez, Adriana PhD |
Bacterial Biofilm Formation in Patients with Chronic Sinusitis | Biostatistical Support |
Pediatrics
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Beauchamp, Belinda MD | Childhood Obesity Study | Biostatistical Support |
| Blasini, Ileana MD | Impact of disclosure of HIV Diagnosis to Children/Adolescents and Families affected by this Chronic Condition. | Biostatistical Support |
| Bonilla Felix, Melvin MD | A Dose-ranging, safety and Pharmacokinetics Study of Candesartan Cilexetil in Hypertensive Pediatrics 1 to less than 6 years of age: A 4-Week, Multicenter, Randomized, Double-Blind Study with a 1-year Open-label, Follow- up Period. |
Laboratory Outpatient |
| Bonilla Felix, Melvin MD | Obstructive Sleep Apnea and Hypertension in Obese Children Between 11-18 years | Biostatistical Support |
Pharmacology
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Báez, Adriana PhD | Head and Neck Cancer in Puerto Ricans: Genetics, Environmental and Clinical Determinants | Biostatistical Support |
Physical Therapy
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Mulero, Ana Leticia PhD | Feasibility of an Exercise Program Among Breast Cancer Survivors in Puerto Rico |
Outpatient Laboratory |
Post Doctoral in Clinical Research
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Carrera, Alberto MD | Factors Impacting the implementation of Rapid HIV Testing in Labor and Delivery: Preventing Perinatal HIV Transmission | Biostatistical Support |
| Hechavarría, Rosa M. PhD | Depression Related to Viral Immune Profile in Hispanic Women with HIV | Biostatistical Support |
Psychology
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Canino, Glorisa PhD | Gene Environment Interplay in Infant development |
Biostatistical Support Laboratory |
| Vera, Mildred PhD | Collaborative Care of Depressed Patients with Chronic Health Conditions | Outpatient |
Public Health
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Bonilla, Luis PhD | Pediatric Asthma care Patient outcomes Research Team. | Biostatistical Support |
| Pérez, Cynthia PhD | Epidemiology of Hepatitis C infection in the household, Adult Population of Puerto Rico. | Laboratory |
Radiological Sciences
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Antonio Algaze Beato, PhD | Functional and Structural Correlates of Neurocognitive Impairment in HIV-(Pilot Project) | Administrative Support |
Rheumatology
|
INVESTIGATOR |
PROTOCOL NAME |
SUPPORT/FACILITIES |
| Martínez, David MD | Asociación entre el cumplimiento de la terapia de medicamentos anti-reumáticos, características demográficas, socioeconómicas, estado funcional, actividad de la enfermedad y daño en pacientes con artritis reumatoide. | Biostatistical Support |
| Martínez, David MD | A Phase III, Multicenter, Randomized, Double blind, Placebo controlled comparative study of Abatacept or Infliximab in combination with Methotrexate in controlling disease activity in subject with Rheumatoid Arthritis having an inadequate clinical response to Methotrexate. (IM101-043) |
Laboratory Outpatient |
| Martínez, David MD | A Phase III, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Use Study to Evaluate the Safety and Tolerability of BMS-188667 Administered Intravenously to Subjects with Active Rheumatoid Arthritis (RA) with or without Medical Co-Morbidities Receiving Disease Modifying Anti-Rheumatic Drugs (DMARDs) and/or Biologics Approved for RA (IM101-031) |
Laboratory Outpatient |
| Rodríguez, Vanessa E. MD | Anticardiolipin Antibodies in Patients with Raynaud's Phenomenon | Biostatistical Support |
| Vilá, Luis M. MD | Lupus in Minority Populations: Nature vs Nurture-Puerto Rico |
Outpatient Biostatistical Support Laboratory |
