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PILOTS PROJECTS AND FUNDED PROPOSALS 2005


INVESTIGATOR

PROTOCOL NAME

SUPPORT/FACILITIES

Inés García, MD Neural Tube Defects and  a 5,10 Methylenetetrahydofolate Reductase Defect in the Puerto Rican Population - Pilot Study  Biostatistical Support
Inés García, MD Folate Metabolism in the Puerto Rican Population - Pilot Study Biostatistical Support
Gloria Reyes, MD The Role of Connexin 26 Gene Mutations in Causing Hearing Impairment in Puerto Rican Population – Pilot Project  Biostatistical Support
José F. Rodríguez-Orengo, PhD Pilot Project: Pharmacological interactions between Zidovudine and Ribavirin in HCV-HIV co-infected patients treated with Rebetron Outpatient
Yohanna De Jesús, MD Respiratory Pathogens in Bronchoalveolar Lavage in Puerto Rican HIV Population - Pilot  Study  Biostatistical Support
Jesús R. Vélez-Borrás, MD Long Term, Open-Label, Safety Study of Tomoxetine Hydrochloride in Patients, 6 Years or Older (LYAI) Outpatient 
Laboratory
Valerie Wojna, MD Estrogen as Neuroprotector Factor in HIV Dementia (Institutional) Outpatient Biostatistical  Laboratory  Support
Carlos A. Luciano, MD HIV Sensory Neuropathy: Age Risk Factors and Immunopathogenesis Outpatient Laboratory Biostatistical Support
Zoe M. Rodríguez-Rivera, MD Safety and Efficacy of Pentavent (G1,G2,G3,G4,and P1) Human-Bovine Reassortant Rotavirus Vaccine in Healthy Infants (Protocol 228-006-00) Laboratory Support
Litsa Morou, DMD, PhD  Urease Activity as an Indicator of Caries Susceptibility in Children Biostatistical Support
Loyda Meléndez, PhD Monocyte Immunity in HIV Induced Dementia Outpatient Biostatistical Support
Carmen Serrano, MD An Active Extension of the TVP-1012/133 Study A Binational Double-Blind, Randomized Study to Evaluate the Safety and Tolerability of Rosagiline Mesylate in Advanced PD Patients with Motors Fluctuations Treated with Chronic Levodopa/Carbidopa Therapy  TVP - 1012/135 Outpatient  Laboratory
Josefina Romaguera, MD Immunogenicity and Safety of Quadrivalent HPV (Types 6, 11, 16, 18) I1 Virus-Like Particle (VLP) Vaccine in Consistency Lots for 16 to 23 Year Old Women with an Additional Immunogenicity Bridge to the Monovalent HIPV 16 Vaccine Pilot Manufacturing Lot – The F.U.T.U.R.E. Study (Females United to Unilaterally Reduce Endo-Ectocervical Disease) Biostatistical  Laboratory  Support
Josefina Romaguera, MD Menopause and Health in Hispanic Women in Puerto Rico Outpatient  Biostatistical Support
Esther Torres, MD, FACP Profile of the Patients evaluated at the Liver Transplant Clinic of the University of Puerto Rico Medical Sciences Campus Biostatistical Support
Donald Dexter, MD Effect of b-agonist on QT Interval in Normals and in Subjects with Pulmonary Obstructive Disease Biostatistical Support
Carmen Cadilla, PhD Molecular Genetics of Hermansky Pudlak Syndrome in Puerto Rico Outpatient
Rafael Burgos, MD Diabetes Reduction Assessment with Ramipril and Rosiglitazone Medication - A Randomized Placebo Controlled Trial  Outpatient Biostatistical Laboratory Support
Luis M. Vilá, MD Lupus in Minority Populations: Nature vs Nurture-Puerto Rico Outpatient Biostatistical Laboratory Support
Loyda Meléndez, PhD The Effect of LPS and cytokines in the surface expression of HIV-1 receptors on placental macrophages and their susceptibility to HIV-1 Infection Biostatistical Support
Ana Leticia Mulero, PhD Feasibility of an Exercise Program Among Breast Cancer Survivors in Puerto Rico Biostatistical Support
Mildred Vera, PhD Collaborative Care of Depressed Patients with Chronic Health Conditions Biostatistical Support
Esther A. Torres, MD Inflammatory Bowel Disease Patient Serum Bank  Laboratory Support
Juan Rivera, MD Infants Short Term Outcome after High Frequency Oscillatory Ventilation Biostatistical Support
Irma Febo, MD Connect to Protect (C2P): Partnerships for Youth Prevention Interventions ATN 016 Biostatistical Support
Lourdes García, MD MTHFR mutations and Homocysteine in Children with Congestive Heart Disease Outpatient Biostatistical Laboratory Support
Lourdes García, MD Folate and Homocysteine Levels in Puerto Rican Women after Mandatory Folic Acid Supplementation of Grain Derived Products Biostatistical Laboratory Support
Glorisa Canino, MD Puerto Rican Neonatal Twin Registry - Pilot Study Funding
Lydia López Del Valle, DMD, MPH Periodontal Disease and Prematurity - Pilot Study Outpatient Laboratory Funding
Iraida Robledo, PhD Susceptibility Patterns and Genotypic Characterization of H. pylori Isolates from PR - Pilot Study Biostatistical Support
Valerie Wojna, MD MRS and HIV Dementia in Puerto Rican Women  Pilot Project Biostatistical Support
Esther Torres, MD Mapping Genes for IBD in Puerto Ricans Outpatient  Biostatistical  Laboratory Support
David Martínez, MD A Phase III, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Use Study to Evaluate the Safety and Tolerability of BMS-188667 Administered Intravenously to Subjects with Active Rheumatoid Arthritis (RA) with or without Medical Co-Morbidities Receiving Disease Modifying Anti-Rheumatic Drugs (DMARDs) and/or Biologics Approved for RA Outpatient Laboratory  Support
Luis Vilá, MD Case Control Study in Systemic Lupus Erythematosus Outpatient Laboratory  Support
Vanessa E. Rodríguez, MD Anticardiolipin Antibodies in Patients with Raynaud's Phenomenon Biostatistical Support
Mikhail Antoun, PhD Clinical and Mechanistics Studies of Lupinus termis Seeds Extract Biostatistical Support
Guillermo Vázquez, MD Detection of Extended-Spectrum Beta Lactamases in E.coli and K.pneumoniae Clinical Isolates from the Puerto Rico Medical Center Biostatistical Support
Miguel Fiol, MD Genetics Studies of Epilepsy Informative Population  Outpatient
Carlos Luciano, MD A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Dose-Ranging Study to Evaluated the Efficacy and Safety of Prosaptide over 6 weeks of Treatment for the Relief of Neuropathic Pain Associated with HIV-1 Outpatient Laboratory Support
Pablo Costas, MD MELD score as a Predictor of Morbidity and Mortality in Patients with Chronic Liver Disease Hospitalized for Acute Variceal Bleeding Biostatistical  Support
Esther Torres, MD Infliximab for Crohn's Disease: Experience at a Puerto Rican Center Biostatistical  Support
Evangelina Morou-Bermudez, DDS, MS, PhD Urease Activity and Dental Caries in Children Pilot Study Funding Laboratory Biostatistical Support
Margarita Irizarry-Ramírez, PhD Proteomic Analysis of the Sera of Prostate Cancer in Hispanics Patients Pilot Study Outpatient Laboratory Funding Biostatistical Support
Valerie Wojna, MD Oxidative Markers in CSF of HIV Demented Women Pilot Study Funding Biostatistical Support
Jesús Vélez-Borrás, MD Olanzapine versus Placebo in the Treatment of Mania in Adolescents with Bipolar Disorder Outpatient Laboratory Support
Francisco Bermúdez, DMD, PhD Oral Cancer Detection: Current and Emerging Technologies Outpatient Laboratory Support
Jorge L. Santana, MD Cerebrospinal Fluid Human Immunodeficiency Virus-1(HIV-1) and Cognitive Function in Individuals Receiving Potent Antiretroviral Therapy Outpatient
Adriana Báez, PhD Head and Neck Cancer in Puerto Ricans: Genetics, Enviromental and Clinical Determinants Biostatistical Support
Lourdes Guerrios, MD The Effectiveness of Duloxetine Compared with Placebo in the Treatment of Predominant Stress Urinary Incontinence  Outpatient
Gishlaine Alfonso, MD Amyotrophic Lateral Sclerosis in Puerto Rico (ALS group)  Biostatistical Support
Gishlaine Alfonso, MD Guillain Barre in Puerto Rico Biostatistical Support
Martha Y. Gómez-Cuellar, MD Prevalence of the Metabolic Syndrome Among a Food Industry Employees in Puerto Rico Biostatistical Support
Esther A. Torres, MD Response to Pegylated Interferon and Ribavirin in Puerto Ricans with Chronic Hepatitis C Biostatistical Support
Humberto Muñoz, MD Response to Combination Therapy of Interferon Alfa-2b plus Ribavirin in Hispanics with Chronic Hepatitis C  Biostatistical Support
Esther A. Torres, MD Anemia in Patients with Ulcerative Colitis and Ileal Pouch Biostatistical Support
Esther A. Torres, MD Retrospective Study of the Management of Esophageal Varices in Cirrhotic Patients Evaluated at ASEM Emergency Room and the University Hospital Biostatistical Support
Esther A. Torres, MD Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor as an Alternative Therapy for Fistulizing Crohn's Disease Biostatistical Support
Marta Valcárcel, MD Early Identification of Stroke and/or Intraventricular Hemorrhage Grade III/IV in Newborns of <=1500 Grams Born in Puerto Rico will Facilitate the Identification of Prothrombotic Disorders in the Neonate Biostatistical Support 
Rafael Burgos Calderón, MD An Open-Label, Randomized, Multicenter, Parallel Group Study To Demostrate Correction Of Anemia Using Subcutaneous Injections of RO0503821 in Patients with Chronic Kidney Disease Who are not on Dialysis Outpatient Laboratory
Marta Rivero, DNS, RN
Dharma Freytes, RN, MSN
Description of Skin Disease in HIV Positive Persons Biostatistical Support
Marta Rivero, DNS, RN Self-Care Symptom Management in HIV/AIDS Biostatistical Support
Mario García-Palmieri, MD Atrial Fibrillation and Congestive Heart Failure Outpatient Laboratory
Ivonne Jiménez, MD A Study of Risk Factors for Alzheimer's Disease and Related Disorders in the Caribbean Hispanic Population in Puerto Rico Outpatient Laboratory
Esther Torres, MD Inflammatory Bowel Disease Serum Bank Laboratory
Mario García-Palmieri, MD Atrial Fibrillation and Congestive Heart Failure Outpatient Laboratory
Ivonne Jiménez, MD A Study of Risk Factors for Alzheimer's Disease and Related Disorders in the Caribbean Hispanic Population in Puerto Rico Outpatient Laboratory
Jorge Santana, MD A phase II study of the predictive value of pharmacokinetic-adjusted phenotypic susceptibility (c12h/ic50 ) on antiretroviral response to ritonavir-enhanced protease inhibitors in subjects with failure of previous protease inhibitor-based regimens ACTG A5126 Outpatient
Valerie Wojna, MD Pathophysiology of HIV dementia Outpatient
Linda Laras, MD, MPH, FACOG Women's Cardiovascular Risk and Violent Experience Biostatistical Support
Rafael Burgos-Calderón, MD  Lisandro Montalvo, MD The role of inflammatory cytokines and oxidative stress and the effect of angiotensin II blockadeon diabetic neuropathy Biostatistical Support
Caleb Feliciano, MD    Rafael Rodríguez, MD Management of Pediatric Cerebrovascular Lesions using Endovascular Techniques  Biostatistical Support
Michael Iñesta, MD Quality of life of Surgical and Internal Medicine Residents at the University of Puerto Rico after new duty hour regulations  Biostatistical Support
Yohanna De Jesús, MD    Ruth Santos, MD Validation of the Spanish Version of the Medical Research Council Scale, Basal Dyspnea Index, Oxygen Cost Diagram, and the San Diego Shortness of Breath Questionnaire in a Hispanic Population  Biostatistical Support
Lourdes C. Irene, MS
Marta Rivero, PhD
Conocimientos, Actitudes y Condiciones Contextuales Relacionadas al uso de Precauciones Estándares para la Prevención de VIH en el Personal de Enfermería Biostatistical Support
Ruth Soto, MD Reiki  in patients with HIV Dementia Biostatistical Support
Alberto Villanueva, MD
Ivonne Jiménez, MD
Effectiveness of Combination Therapy  with Memantine and Donepezil in the Treatment of mild Alzheimer disease in Puerto Rico Biostatistical Support
Alberto Vázquez, MD Ivonne Jiménez, MD Women's Cardiovascular Risk and Violent Experience Biostatistical Support
 

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